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11.
For a structure formed from two thin-walled open members connected at 90°, torsion applied to one member can result in torsion as well as flexure in the second member, with the magnitude and direction of this torsion as well as flexure in the second member being determined by the type of joint used. Conventional structural analysis would normally assume the presence of only flexure in the second member. The results from a finite element study of structures formed from thin-walled channel sections connected by box, mitre and stiffened mitre joints is presented and an explanation for the behaviour of the different joint types is given. It is shown that for the box joint the warping deformation of the loaded member is the dominant factor in determining the magnitude and direction of the twisting of the second member, whilst this is determined for the stiffened mitre joint primarily by the St Venant rotation deformation of the loaded member. For the unstiffened joint it is shown that the warping and St Venant rotation deformation effects tend to cancel each other out.  相似文献   
12.
IGF-1 and its receptors have been identified in many tissues including the central nervous system (CNS). We have previously demonstrated that injection of insulin directly into the cerebral ventricles (ICV) is followed by a drop in mean arterial pressure (MAP) associated with an increase in skeletal muscle blood flow. Given the similarities between the IGF-1 and insulin molecules and their respective receptors, we have investigated the effect of ICV administration of IGF-1 on systemic blood pressure and blood flow in selected vascular beds. ICV cannulas were implanted into normal rats and the animals were allowed to recover for 3 to 4 days. The femoral artery and vein were cannulated for blood pressure monitoring and blood sampling and blood flow probes placed around the iliac, the renal and the superior mesenteric artery were used to assess regional blood flow. ICV injection of IGF-1 resulted in a significant decrease in MAP with a nadir at 15 minutes and a gradual return to baseline by 60 minutes; heart rate increased 40 minutes after the injection. IGF-1 significantly enhanced vascular flow and conductance in the iliac, but not in the renal and superior mesenteric arteries. The effects of IGF-1 were much smaller than those observed previously with equimolar amounts of insulin. We conclude that IGF-1 can decrease MAP by selectively increasing blood flow to skeletal muscle through a direct action on the central nervous system.  相似文献   
13.
Traditional economic evaluation methods concentrate on maximizing or minimizing a single objective such as net present value and pay back period. In the last decade, there has been an increased awareness of the need to consider multiple attributes in the evaluation of advanced manufacturing systems. Various methods have recently been developed for the evaluation of CIM systems. This paper discusses multiattribute methods for justification of CIM systems and outranking methods including ELECTRE, ORESTE, and PROMETHEE.  相似文献   
14.
Fretting fatigue is one of the most important phenomena for inducing a significant reduction of fatigue strength and consequently, leading to unexpected failure accidents of the engineering structures even at very low stresses. In the present study, both plain and fretting fatigue tests with zero mean stress were carried out on two different types of steel, low-carbon steel and martensitic stainless steel, by means of a reversed bending fatigue testing machine. The drop in the fatigue strengths through fretting at vise clamp-specimen interface were significant for both tested steels. The fretting processes produced a reduction in fatigue strength of about 27% for low-carbon steel and 16% for martensitic stainless steel.  相似文献   
15.
Poly(methyl methacrylate) (PMMA) gels with varying amounts of silicone and solvent and constant amounts of crosslinker were prepared by solution free radical crosslinking copolymerization of methyl methacrylate (MMA), ethylene glycol dimethacrylate (EGDM), tetraethoxysilane (TEOS) and vinyltriethoxysilane (VTES) comonomer systems. They were then studied in benzene at a total monomer concentration of 3.5 mol L?1 and 70 °C. The conversion of monomer, volume swelling ratio, weight fraction and gel point were measured as a function of the reaction time, silicone concentration and benzene content up to the onset of macrogelation. Structural characteristics of the gels were examined by using equilibrium swelling in benzene, gel fraction and Fourier‐transform infrared (FTIR) analysis. The morphology of the copolymers was also investigated by SEM. Based on the obtained results, it was concluded that the FTIR data did not have the capacity to show the presence of the VTES or TEOS moiety in these kinds of copolymers. On the other hand, the variation of weight fraction of gel, Wg, and its equilibrium volume swelling ratio in benzene, qv, exhibited the same behaviour as that of MMA/EGDM copolymers. Also, the dilution of the monomer mixture resulted in an increase in the gel point and swelling degree and a decrease in the percent of conversion and gel fraction. Finally, TEOS is not an ideal silicone compound for reaction in the MMA/EGDM copolymerization system, whereas VTES is a suitable silicone comonomer for this system and it has been proved useful. Copyright © 2005 Society of Chemical Industry  相似文献   
16.
In this study the electrical and mechanical properties of microfibrillar polypropylene (PP)/polyamide6 (PA6) blend filled with super conductive carbon black (CB) have been investigated. In situ microfibrillar PP/PA6 composites filled with CB are produced using a single screw extruder equipped with a spinneret. Glycidyl methacrylate (GMA) grafted polypropylene (PP-g-GMA) is used as the compatibilizer. To investigate the effects of extensional flow on the microstructure, electrical and mechanical properties, three adaptors with various convergence angles were designed, prepared and applied between the extruder and the spinneret. To optimize the effects of processing and material parameters on the electrical and mechanical properties, the Taguchi method of experimental design is used. Material and processing factors which are studied include: concentration of PA6, compatibilizer level, CB concentration, drawing speed of melt spinning line, adaptor angle, order of mixing and temperature profile along the extruder. The results show an increase in DC conductivity of up to 1011 times in comparison with pure PA6, by increasing the concentration of CB, drawing speed, adaptor angle and optimizing other parameters. By optimizing processing and material factors studied here, strength of microfibrillar structured composites is increased of up to 80% in comparison to pure PP.  相似文献   
17.
The usage of wood‐plastic composites (WPCs) is rapidly growing because of their many advantages. However, they still suffer from lack of strength and toughness, which can be improved by adding a small amount of glass fiber reinforcement (GFR). Tensile tests of high‐density polyethylene WPC specimens with varying amounts of wood fiber content and 5% of GFR were carried out. Significant improvements in properties were observed. J. VINYL ADDIT. TECHNOL., 2008. © 2008 Society of Plastics Engineers.  相似文献   
18.
Studies in laboratory animals have demonstrated that dietary supplements of organoselenium, 1,4-phenylenebis(methylene)selenocyanate (p-XSC) inhibit colon carcinogenesis. Diverse chemopreventive agents and clinically used anticancer drugs have been shown to induce apoptosis in colonic tumors. Inducing apoptosis is a key mechanism for the effectiveness of some chemopreventive agents; however, failure of apoptosis is now believed to contribute to the development of human cancer. In this study, we determined the number of apoptotic bodies in the colon tumors of rats fed a low-fat (LF) or a high-fat (HF) diet with or without p-XSC treatment. At 5 weeks of age, male F344 rats were divided into four groups, which were then maintained on one of the following diets: LF, 5% corn oil; HF, 23.5% corn oil; and LF and HF supplemented with 20 ppm p-XSC. In addition, the LF or HF diet with p-XSC supplements was administered either during the initiation stage or postinitiation. At 7 weeks of age, all rats except those intended for vehicle (normal saline) treatment were given 15 mg/kg of body weight of azoxymethane once weekly for 2 weeks. The animals were sacrificed 38 weeks after carcinogen treatment, and their colonic tumors were examined for appearance of apoptosis. The LF diet significantly increased the percentage of apoptosis as compared to the HF diet; the percentage of apoptosis in LF and HF diets were 12.4 and 2.9. The colon tumors that were present in the groups fed p-XSC together with a LF or a HF diet after carcinogen administration (postinitiation period) had a higher number of apoptotic bodies than those that were present in the animals fed p-XSC before carcinogen treatment (initiation period). The extent of apoptosis was weak when p-XSC was given with a HF diet (4.4%) during the initiation phase, but it was high significant when p-XSC was administered with LF diet (25.2%). Taken together, our data suggest that administration of LF diet supplemented with p-XSC increases apoptosis as compared to a HF diet alone.  相似文献   
19.
20.
Effect of glucose concentration and the inhibition of carotenoids on the lipids synthesis by Micrococcus colpogenes were studied. It was observed that the maximum lipid production was obtained when 2 % glucose was used as carbon source. The inhibition of carotenoids with diphenylaminc (25 mg/L) showed 37 % increase in the lipid synthesis.  相似文献   
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